Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143658 | 0.88 | TSHR (0.67) | TSHRCYP3A4ALOX5TP53KMT2A | |
| SCHEMBL10383327 | 0.81 | CA1 (0.55) | TSHRKMT2ACA12CA1CA2 | |
| SCHEMBL16771272 | 0.79 | TSHR (0.67) | TSHRTP53KMT2ACA12CA1 | |
| Acedoben SCHEMBL24320 | 0.75 | ALDH1A1 (0.68) | TSHRCYP3A4TP53KMT2ACA12 | |
| SCHEMBL12137649 | 0.75 | TSHR (0.55) | TSHRTP53KMT2ACA12CA1 | |
| Acedoben SCHEMBL11793874 | 0.74 | ALDH1A1 (0.66) | TSHRCYP3A4TP53KMT2ACA12 | |
| Acedoben SCHEMBL11274912 | 0.74 | ALDH1A1 (0.66) | TSHRCYP3A4TP53KMT2ACA12 | |
| Acedoben SCHEMBL3464430 | 0.74 | ALDH1A1 (0.66) | TSHRCYP3A4TP53KMT2ACA12 | |
| Acedoben SCHEMBL1458995 | 0.74 | ALDH1A1 (0.66) | TSHRCYP3A4TP53KMT2ACA12 | |
| Acedoben SCHEMBL9724003 | 0.73 | MAPT (0.77) | TSHRCYP3A4TP53KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |