SCHEMBL10384451

SCHEMBL10384451

Brc1ccccc1-c1c(Br)ccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.50
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPK1 P28482 1/20 0.41
HPRT1 P00492 1/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 3/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
WDR5 P61964 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
CES1 P23141 1/20 0.38
KMT2A Q03164 3/20 0.38
C1R P00736 1/20 0.38
CYP1A2 P05177 1/20 0.37
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369327 0.88 DNMT1 (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30125426 0.88 DNMT1 (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1239327 0.84 ALDH1A1 (0.55) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30361992 0.84 ALDH1A1 (0.55) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL24316338 0.82 CYP2A6 (0.47) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL28769245 0.82 DNMT1 (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29674891 0.82 CYP2A6 (0.48) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL13966913 0.82 CYP2A6 (0.48) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL18174238 0.82 POLB (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL18260194 0.81 DNMT1 (0.44) DNMT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836193-A Organic compound, application thereof and organic electroluminescent device comprising same 清华大学 2023-10-03 CN disclosed
CN-116178436-A Phosphorus-containing polycyclic light-emitting compound, preparation method thereof and organic electroluminescent device 奥来德(上海)光电材料科技有限公司 2023-05-30 CN disclosed
US-4898802-A Toner compositions with organo boron negative charge enhancing additives XEROX CORPORATION (US) 1990-02-06 US disclosed