Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | ALAD | P13716 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 7/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384771 | 0.83 | HDAC6 (0.63) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL1286671 | 0.79 | HDAC6 (0.62) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL27623993 | 0.78 | HDAC6 (0.66) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL505511 | 0.78 | ALAD (0.70) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL3050661 | 0.75 | HDAC6 (0.62) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL6848247 | 0.75 | HDAC6 (0.62) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL5605556 | 0.75 | HDAC6 (0.62) | HDAC6ALADMMP12CYP2C9MMP13 | |
| SCHEMBL6879747 | 0.75 | HDAC6 (0.57) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL6455459 | 0.75 | HDAC6 (0.57) | HDAC6ALADMMP12MMP13USP30 | |
| SCHEMBL2326735 | 0.75 | HDAC6 (0.57) | HDAC6ALADMMP12MMP13HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |