Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959728 | 1.00 | KMT2A (0.54) | KMT2AMAPTNPSR1PLK1PLK3 | |
| SCHEMBL7203391 | 0.95 | KMT2A (0.56) | KMT2AMAPTNPSR1PLK1PLK3 | |
| SCHEMBL29511376 | 0.95 | KMT2A (0.56) | KMT2AMAPTNPSR1PLK1PLK3 | |
| SCHEMBL5952645 | 0.89 | KMT2A (0.59) | KMT2AMAPTNPSR1HCAR3HTT | |
| SCHEMBL6623104 | 0.88 | NPC1 (0.54) | KMT2AMAPTPLK1PLK3HCAR3 | |
| SCHEMBL3850700 | 0.84 | KMT2A (0.65) | KMT2AMAPTNPSR1HCAR3HTT | |
| SCHEMBL5870594 | 0.83 | RAB9A (0.52) | KMT2AMAPTPLK1PLK3HCAR3 | |
| SCHEMBL9739647 | 0.83 | MAPT (0.57) | KMT2AMAPTNPSR1HTTNPC1 | |
| SCHEMBL5562681 | 0.82 | KMT2A (0.47) | KMT2AMAPTPLK1PLK3HCAR3 | |
| SCHEMBL9365460 | 0.82 | NPC1 (0.47) | KMT2AMAPTNPSR1PLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904712-A | PHOTOSTABILIZERS/AGENTS/ | CIBA-GEIGY CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| US-4847367-A | PHOTOSTABILIZERS, CHEMICAL INTERMEDIATE | CIBA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| US-4727158-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |