SCHEMBL10384752

SCHEMBL10384752

CCOC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.52
GSTK1 Q9Y2Q3 1/20 0.52
DPP4 P27487 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
DPP9 Q86TI2 1/20 0.43
GLO1 Q04760 1/20 0.39
GAA P10253 1/20 0.38
BMP1 P13497 1/20 0.37
FOLH1 Q04609 1/20 0.37
ENPEP Q07075 4/20 0.36
ANPEP P15144 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594416 0.86 PTGS1 (0.48) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL27922442 0.86 PTGS1 (0.55) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL30700928 0.85 PTGS1 (0.52) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL20587887 0.84 DPP4 (0.49) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL6010631 0.84 DPP4 (0.49) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL4400076 0.84 DPP4 (0.49) PTGS1GSTK1DPP4DPP8DPP9
Glutathione Ethyl Ester SCHEMBL7530345 0.84 PTGS1 (0.71) PTGS1GSTK1GLO1L3MBTL1KMT2A
Glutathione Ethyl Ester SCHEMBL680361 0.84 PTGS1 (0.71) PTGS1GSTK1GLO1L3MBTL1KMT2A
Glutathione Ethyl Ester SCHEMBL9817298 0.84 PTGS1 (0.71) PTGS1GSTK1GLO1L3MBTL1KMT2A
SCHEMBL931787 0.84 PTGS1 (0.70) PTGS1GSTK1DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381219-A1 HYPERTONIC PHARMACEUTICAL COMPOSITIONS CONTAINING AN ANTI-PLATINUM CHEMOPROTECTANT AGENT DECIBEL THERAPEUTICS INC (US) 2025-12-18 US disclosed
US-4927808-A GLUTATHIONE LEVELS IN TISSUES TEIJIN LIMITED (JP) 1990-05-22 US disclosed
EP-0276317-A1 GAMMA-L-GLUTAMYL-L-CYSTEINE ETHYL ESTER AND DRUG CONTAINING IT AS EFFECTIVE INGREDIENT TEIJIN LIMITED (JP) 1988-08-03 EP disclosed