Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20587887 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL4400076 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL4400081 | 0.89 | DPP4 (0.49) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL6010639 | 0.89 | DPP4 (0.49) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL930492 | 0.85 | CAD (0.42) | PTGS1L3MBTL1NOD1KMT2APOLB | |
| SCHEMBL8644441 | 0.85 | CAD (0.42) | PTGS1L3MBTL1NOD1KMT2APOLB | |
| SCHEMBL10384752 | 0.84 | PTGS1 (0.52) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL210006 | 0.82 | FOLH1 (0.62) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL536354 | 0.82 | FOLH1 (0.62) | DPP4DPP8DPP9PTGS1GSTK1 | |
| SCHEMBL210315 | 0.82 | FOLH1 (0.62) | DPP4DPP8DPP9PTGS1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701732-A2 | SULFHYDRYL PROTECTED GLUTATHIONE PRODRUG | Nagasawa, Herbert T. (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005074903-A2 | SULFHYDRYL PROTECTED GLUTATHIONE PRODRUG | NAGASAWA HERBERT T (US) | 2005-08-18 | — | — | WO | disclosed |