SCHEMBL10385271

SCHEMBL10385271

CCCC1CCC(CCc2ccc(-c3ccccc3)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.46
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10385270 1.00 HRH3 (0.46) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL10899256 0.93 MAOB (0.47) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL10899249 0.93 MAOB (0.47) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL11060529 0.89 MAOB (0.53) HRH3MAOAMAOB
SCHEMBL11060533 0.89 MAOB (0.53) HRH3MAOAMAOB
SCHEMBL10901701 0.89 MAOB (0.53) HRH3MAOAMAOB
SCHEMBL9346297 0.89 HRH3 (0.54) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL1031533 0.89 HRH3 (0.54) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL10383559 0.89 HSD11B1 (0.47) HRH3MAOAMAOBCARM1PRMT6
SCHEMBL10383558 0.89 HSD11B1 (0.47) HRH3MAOAMAOBCARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935160-A Liquid-crystal guest-host systems MERCK PATENT GESSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-19 US disclosed