Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 6/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.54 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385461 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL10746056 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL10746061 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL9225216 | 0.91 | SMN1; SMN2 (0.64) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL9225209 | 0.91 | SMN1; SMN2 (0.64) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL5177047 | 0.91 | CTSS (0.56) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL29437121 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL36611 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| SCHEMBL8496964 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2CTSSCTSLCTSKCTSB | |
| Hydroxyamine SCHEMBL9197242 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908452-A | Reacting carboxamide with carboxysulfamoylammonium hydroxide to effect dehydration to form the corresponding nitrile | MERCK & CO., INC. (US) | 1990-03-13 | — | — | US | disclosed |