Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164361 | 0.73 | TSHR (0.45) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL29581427 | 0.73 | TSHR (0.45) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL2131884 | 0.73 | TSHR (0.45) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL26222955 | 0.73 | TSHR (0.45) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL29025450 | 0.73 | TSHR (0.45) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL6049869 | 0.72 | TSHR (0.50) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL30407772 | 0.72 | GABRA1 (0.58) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL5496813 | 0.72 | GABRA1 (0.58) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL30337376 | 0.72 | TSHR (0.50) | TSHRACHEGABRA1GABRB2TDP1 | |
| SCHEMBL8784146 | 0.72 | TSHR (0.50) | TSHRACHEGABRA1GABRB2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973660-A | Polyamide of diamino-t-butyltoluene | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | claimed |
| US-4963648-A | SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-10-16 | — | — | US | claimed |
| US-4973660-A | Polyamide of diamino-t-butyltoluene | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| US-4973660-A | Polyamide of diamino-t-butyltoluene | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| US-4973660-A | Polyamide of diamino-t-butyltoluene | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| US-4963648-A | SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4963648-A | SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4963648-A | SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |