SCHEMBL10385652

SCHEMBL10385652

CCOC(=O)CC(C(=O)OCC)C1C=C(CC)C(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10385212 0.92 CYP2D6 (0.31) CYP2D6
SCHEMBL10385648 0.88
SCHEMBL10385175 0.88 CYP2D6 (0.41) CYP2D6ALDH1A1TSHR
SCHEMBL10385657 0.81 DNTT (0.31)
SCHEMBL10384932 0.79 CYP2D6 (0.32) CYP2D6
SCHEMBL10385654 0.78 MAPT (0.32)
SCHEMBL10386816 0.76 CYP2D6 (0.45) CYP2D6ALDH1A1TSHR
SCHEMBL10385656 0.76 DNTT (0.35)
SCHEMBL10385650 0.75 CYP2D6 (0.40) CYP2D6ALDH1A1TSHR
SCHEMBL10386803 0.71 CYP2D6 (0.47) CYP2D6ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4952611-A AROMATIC DIAMINES AND ESTERS OF TETRACARBOXYLIC ACUDS ABD DICARBOXYLIC CYCLOHEXENYL SUCCINIC ACID ETHYL CORPORATION (US) 1990-08-28 US disclosed
EP-0343999-A1 Polyimide foams and their production ETHYL CORPORATION (US) 1989-11-29 EP disclosed
US-4855332-A 2-/VICINAL-DICARBOXYCYCLOHEXENYUL/SUCCINIC ACID ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4826886-A AIRCRAFT SEAT CUSHIONS ETHYL CORPORATION (US) 1989-05-02 US disclosed