SCHEMBL10385656

SCHEMBL10385656

CCCCC1=CC(C(CC(=O)OC)C(=O)OC)CC(C(=O)O)C1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNTT P04053 5/20 0.35
POLB P06746 4/20 0.33
POLA1 P09884 4/20 0.33
PTGER2 P43116 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10385210 0.89
SCHEMBL10385657 0.84 DNTT (0.31) DNTTPOLBPOLA1
SCHEMBL10385648 0.76
SCHEMBL10385652 0.76 CYP2D6 (0.40)
SCHEMBL10385212 0.72 CYP2D6 (0.31)
SCHEMBL10385205 0.71
SCHEMBL11112005 0.71 CYP3A4 (0.32) POLB
SCHEMBL10385175 0.71 CYP2D6 (0.41)
SCHEMBL10386735 0.70 CYP2D6 (0.32)
SCHEMBL10535895 0.69 CYP2D6 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4952611-A AROMATIC DIAMINES AND ESTERS OF TETRACARBOXYLIC ACUDS ABD DICARBOXYLIC CYCLOHEXENYL SUCCINIC ACID ETHYL CORPORATION (US) 1990-08-28 US disclosed
EP-0343999-A1 Polyimide foams and their production ETHYL CORPORATION (US) 1989-11-29 EP disclosed
US-4866104-A FLEXIBILITY, SOFTNESS ETHYL CORPORATION (US) 1989-09-12 US disclosed
US-4855332-A 2-/VICINAL-DICARBOXYCYCLOHEXENYUL/SUCCINIC ACID ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4826886-A AIRCRAFT SEAT CUSHIONS ETHYL CORPORATION (US) 1989-05-02 US disclosed