Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 8/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224738 | 0.81 | KLK7 (0.40) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL28451513 | 0.80 | KLK7 (0.40) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL21104039 | 0.80 | KLK7 (0.40) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL10386697 | 0.78 | KLK7 (0.61) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL10387214 | 0.78 | KLK7 (0.61) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL18593027 | 0.76 | MAPK1 (0.43) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL27635233 | 0.76 | MAPK1 (0.43) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL4663361 | 0.76 | KLK7 (0.52) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734949 | 0.75 | KLK7 (0.37) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734866 | 0.73 | KLK7 (0.36) | KLK7KLK5PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978759-A | REACTING MELDRUM*S ACID WITH PROTECTED AMINO ACID, CYCLIZATION DECYCLIZING, REDUCTION AND DEPROTECTING; STATINE | SANOFI, S.A. AND INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1990-12-18 | — | — | US | disclosed |