Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18593027 | 1.00 | MAPK1 (0.43) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL31750269 | 0.82 | KLK7 (0.36) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL34473806 | 0.82 | KLK7 (0.36) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL16224738 | 0.80 | KLK7 (0.40) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL22096754 | 0.77 | KLK7 (0.40) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL34473950 | 0.76 | KLK7 (0.35) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL10387166 | 0.76 | KLK7 (0.40) | MAPK1KLK7MAPTKLK5PRSS1 | |
| SCHEMBL28451513 | 0.75 | KLK7 (0.40) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL21104039 | 0.75 | KLK7 (0.40) | MAPK1KLK7KDM4EMAPTTHRB | |
| SCHEMBL13409204 | 0.74 | USP2 (0.40) | MAPK1KLK7KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |