Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935606 | 0.86 | HTT (0.69) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL10387534 | 0.83 | LMNA (0.70) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL10387958 | 0.82 | SMN1; SMN2 (0.65) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL10349497 | 0.82 | HTT (0.58) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL10349671 | 0.81 | HTT (0.57) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL10387980 | 0.79 | MAPK1 (0.69) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL6957110 | 0.78 | MAPK1 (0.62) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL17677816 | 0.78 | GRK2 (0.64) | HTTSMN1; SMN2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6956607 | 0.77 | HTT (0.63) | HTTSMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL6418277 | 0.77 | LMNA (0.71) | HTTSMN1; SMN2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973691-A | ANALGESICS | Spojene Podniky Prozdravotnickou Vyrobu (SPOFA) (CS) | 1990-11-27 | — | — | US | disclosed |
| US-4973691-A | ANALGESICS | Spojene Podniky Prozdravotnickou Vyrobu (SPOFA) (CS) | 1990-11-27 | — | — | US | disclosed |