Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.73 |
| ▸ | YAP1 | P46937 | 1/20 | 0.73 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.73 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492938 | 0.83 | TEAD1 (0.73) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL11309511 | 0.78 | HPGD (0.69) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18775352 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8015226 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14241835 | 0.75 | TEAD1 (0.77) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL10388479 | 0.74 | KDM4E (0.45) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL9808073 | 0.74 | TEAD1 (0.60) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL9925290 | 0.74 | HPGD (0.62) | HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL10389706 | 0.73 | NPC1 (0.67) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL9808086 | 0.72 | TEAD1 (0.58) | TEAD1YAP1TEAD4TEAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892952-A | Substituted heteroaralkyl, heteroaralkenyl or halomethyl fungicides | CHEVRON RESEARCH COMPANY (US) | 1990-01-09 | — | — | US | disclosed |