Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388918 | 1.00 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10388896 | 0.88 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10388898 | 0.88 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10389527 | 0.87 | MAPT (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10389529 | 0.87 | MAPT (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9833103 | 0.84 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3614705 | 0.84 | THRB (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3614708 | 0.84 | THRB (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9833107 | 0.84 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5059085 | 0.83 | CA12 (0.86) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978523-A | P-hydroxycinnamides to remove pigment deposits in skin | KAO CORPORATION (JP) | 1990-12-18 | — | — | US | disclosed |