Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390295 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL10390075 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL10391193 | 0.76 | KMT2A (0.56) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11661676 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL2309848 | 0.69 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8104878 | 0.69 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRNMT2 | |
| SCHEMBL10390172 | 0.68 | KMT2A (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4069381 | 0.68 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10408231 | 0.67 | HTR1B (0.61) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11809140 | 0.67 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10HPGDPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |