Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819296 | 0.85 | HTT (0.51) | TDP1POLBGAAMEN1KMT2A | |
| SCHEMBL18614953 | 0.85 | NOTUM (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25370949 | 0.83 | MRGPRX4 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL757447 | 0.83 | LOXL2 (0.64) | KDM4ETDP1L3MBTL1CYP3A4MEN1 | |
| SCHEMBL1427802 | 0.81 | LOXL2 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4503220 | 0.81 | KDM4E (0.44) | KDM4ETDP1L3MBTL1CYP3A4MEN1 | |
| Bromide SCHEMBL28224566 | 0.80 | LOXL2 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22469960 | 0.79 | MAPT (0.41) | KDM4ETDP1L3MBTL1POLBCYP3A4 | |
| SCHEMBL3542435 | 0.79 | KDM4E (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20377195 | 0.79 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975490-A | Phthalic acid ester-modified organopolysiloxane and method for its preparation | TORAY SILICONE COMPANY, LTD. (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4924020-A | Phthalic acid ester-modified organopolysiloxane and method for its preparation | TORAY SILICON COMPANY, LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0316915-A2 | Phthalic acid ester-modified organopolysiloxane and method for its preparation | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-05-24 | — | — | EP | disclosed |