Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL5694634 | 0.96 | TSHR (0.32) | TSHR | |
| Ether SCHEMBL8491590 | 0.94 | ALDH1A1 (0.32) | — | |
| Ether SCHEMBL608647 | 0.94 | TSHR (0.31) | TSHR | |
| Ether SCHEMBL11122550 | 0.93 | ALDH1A1 (0.31) | — | |
| Ether SCHEMBL17873400 | 0.92 | TSHR (0.30) | TSHR | |
| Ether SCHEMBL6919350 | 0.92 | TSHR (0.30) | TSHR | |
| Alcohol SCHEMBL181400 | 0.92 | TSHR (0.33) | TSHR | |
| Alcohol SCHEMBL367811 | 0.90 | TSHR (0.32) | TSHR | |
| Sulfuric Acid SCHEMBL8764168 | 0.90 | TSHR (0.32) | TSHR | |
| Alcohol SCHEMBL10998216 | 0.90 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923635-A | Liquid detergent composition containing alkylbenzene sulfonate, alkyl ethanol ether sulfate, alkanolamide foam booster and magnesium and triethanolammonium ions | COLGATE-PALMOLIVE COMPANY (US) | 1990-05-08 | — | — | US | disclosed |