Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393443 | 0.89 | ALDH1A1 (0.50) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8342039 | 0.83 | HTT (0.58) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24303662 | 0.81 | ALDH1A1 (0.54) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31117068 | 0.81 | HTT (0.77) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2360995 | 0.80 | NPC1 (0.45) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30254199 | 0.80 | ALDH1A1 (0.52) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10394019 | 0.79 | HTT (0.54) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10393454 | 0.79 | HTT (0.57) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10394640 | 0.79 | HTT (0.54) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL16694907 | 0.74 | HTT (0.54) | HTTALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015983-B | Process for preparing gametocides pyrazoles | LILLY CO ELI (US) | 1992-03-25 | — | — | CN | disclosed |
| US-4966623-A | POLLEN INHIBITION | ACKMANN STEPHEN A (US) | 1990-10-30 | — | — | US | disclosed |
| US-4902808-A | HYBRID, POLLEN FORMATION INHIBITOR | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4801326-A | PRODUCTION OF HYBRID SEED | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| CN-87102443-A | Cametocidal pyrazoles | — | 1987-10-14 | — | — | CN | disclosed |