Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395341 | 0.93 | MEN1 (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10394648 | 0.92 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5654395 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL59653 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL2048930 | 0.75 | ALDH1A1 (0.57) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9402020 | 0.75 | KMT2A (0.45) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7557950 | 0.75 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL17743745 | 0.75 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL5390679 | 0.75 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4324562 | 0.73 | MAPK9 (0.52) | MEN1KMT2AMAPTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973599-A | ANTIINFLAMMATORY AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-11-27 | — | — | US | disclosed |