Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898297 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ATSHRPHGDH | |
| SCHEMBL8898194 | 0.86 | PHGDH (0.44) | ALDH1A1MAPTKMT2ATSHRPHGDH | |
| SCHEMBL9315455 | 0.86 | GSK3B (0.49) | ALDH1A1MAPTKMT2ATSHRHPGD | |
| SCHEMBL8898821 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ATSHRPHGDH | |
| SCHEMBL8899699 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1MAPTKMT2ATSHRPHGDH | |
| SCHEMBL8900790 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8897354 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2ATSHRHPGD | |
| SCHEMBL8899742 | 0.83 | SMN1; SMN2 (0.42) | ALDH1A1MAPTKMT2ATSHRHPGD | |
| SCHEMBL8897848 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2ATSHRHPGD | |
| SCHEMBL8897353 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKMT2ATSHRPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943662-A | SULPHYDROLYSIS | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1990-07-24 | — | — | US | disclosed |