Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 1.00 |
| ▸ | SLC1A1 | P43005 | 7/20 | 1.00 |
| ▸ | SLC1A3 | P43003 | 5/20 | 1.00 |
| ▸ | GRIK1 | P39086 | 4/20 | 1.00 |
| ▸ | GRIK2 | Q13002 | 4/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039722 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL20838572 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5281450 | 1.00 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5324679 | 0.88 | GRIK1 (0.78) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL2267187 | 0.88 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL8764560 | 0.88 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL17874870 | 0.88 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL4379766 | 0.88 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL12611015 | 0.86 | CHRM1 (0.83) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL20838575 | 0.86 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445323-B1 | PROCESS FOR PRODUCING GLUTAMIC ACID DERIVATIVES | AJINOMOTO KK (JP) | 2011-01-26 | — | — | EP | disclosed |