SCHEMBL4379766

SCHEMBL4379766

CCCCC(C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 7/20 1.00
SLC1A1 P43005 6/20 1.00
SLC1A3 P43003 5/20 1.00
GRIK1 P39086 4/20 0.89
GRIK2 Q13002 4/20 0.89
CA2 P00918 1/20 0.61
MAPK1 P28482 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17874870 1.00 SLC1A2 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL8764560 1.00 SLC1A2 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL2267187 1.00 SLC1A2 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL20838575 0.94 SLC1A2 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL8091382 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL9005462 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL5888741 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL1662288 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL4377664 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL8386178 0.92 GRIK1 (1.00) SLC1A2SLC1A1SLC1A3GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60211452-A None JP disclosed
EP-2801379-B1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO CORP (JP) 2017-03-08 EP disclosed
EP-1748805-B1 ABSORBABLE BIOCOMPATIBLE COATINGS BIOINTERACTIONS LTD (GB) 2009-07-29 EP disclosed
EP-1748805-A1 ABSORBABLE BIOCOMPATIBLE MATERIALS Biointeractions Ltd. (GB) 2007-02-07 EP disclosed
US-20060134166-A1 Absorbable biocompatible materials BIOINTERACTIONS LTD. (GB) 2006-06-22 US disclosed
WO-2005115492-A1 ABSORBABLE BIOCOMPATIBLE MATERIALS BIOINTERACTIONS LTD (GB) 2005-12-08 WO disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
US-4679911-A Optical apparatus using liquid crystals for shaping the spatial intensity of optical beams having designated wavelengths THE UNIVERSITY OF ROCHESTER (US) 1987-07-14 US disclosed
US-4637896-A CHOLESTERIC, PHOTOPOLYMERIZATION, PHOTOINITIATORS, (METH) ACRYLATE DERIVATIVES OF (DIHYDRO)CHOLESTEROL ARMSTRONG WORLD INDUSTRIES, INC. (US) 1987-01-20 US disclosed
US-4614619-A Liquid crystalline materials useful to prepare polymeric films ARMSTRONG WORLD INDUSTRIES, INC. (US) 1986-09-30 US disclosed
JP-S60211452-A SILVER HALIDE PHOTOSENSITIVE MATERIAL FUJI PHOTO FILM CO LTD 1985-10-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060134166-A1 Absorbable biocompatible materials ADM2, HDGF, SLC7A1 SLC1A2 125/4885SLC1A1 77/4885SLC1A3 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.