Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397300 | 0.84 | CA12 (0.70) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL38649 | 0.84 | CA12 (0.70) | KDM4EMAPTALDH1A1CA12CA1 | |
| SCHEMBL10398689 | 0.84 | ALDH1A1 (0.52) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL10398430 | 0.84 | ALDH1A1 (0.52) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL10397941 | 0.84 | ALDH1A1 (0.52) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL1965809 | 0.79 | CA12 (0.53) | KDM4ELMNAMAPTALOX15ALOX12 | |
| SCHEMBL10398469 | 0.78 | CA12 (0.70) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL10398443 | 0.78 | CA12 (0.49) | KDM4EALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL10397923 | 0.78 | ALDH1A1 (0.62) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL9724886 | 0.76 | CA12 (0.67) | MEN1LMNAMAPTALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965395-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0224592-B1 | P-HYDROXYBENZOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0224592-A1 | p-HYDROXYBENZOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-06-10 | — | — | EP | disclosed |