Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449011 | 0.86 | TPMT (0.48) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27797687 | 0.85 | TPMT (0.42) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27383638 | 0.85 | KDM4E (0.43) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27400020 | 0.85 | TPMT (0.42) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL583916 | 0.85 | PTGS1 (0.42) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27797720 | 0.85 | TPMT (0.42) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27573333 | 0.84 | GABRP (0.48) | TPMTALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL3097749 | 0.83 | TPMT (0.56) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27567159 | 0.82 | TPMT (0.39) | TPMTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28013312 | 0.82 | TPMT (0.39) | TPMTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889224-A | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS INC | 2014-06-25 | — | — | CN | claimed |
| WO-2019156667-A1 | SHAPE MEMORY COMPOSITES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2019-08-15 | — | — | WO | disclosed |
| CN-103889224-A | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS INC | 2014-06-25 | — | — | CN | disclosed |
| CN-102753527-A | Cyclohexyl amide derivatives as crf receptor antagonists | NOVARTIS AG | 2012-10-24 | — | — | CN | disclosed |
| CN-101519372-B | Benzo [e] isoindazole-1,3 diketone compound used as GSK inhibiting agent and preparation method thereof | SHENZHEN SHENGJIE BIOLOGY TECHNOLOGY CO LTD | 2011-07-20 | — | — | CN | disclosed |
| EP-1318176-B1 | Color enhancement for resin blends | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-01-26 | — | — | EP | disclosed |
| CN-101959882-A | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-7763646-B2 | Compounds for the treatment of alzheimer's disease | ELAN PHARMACEUTICALS, INC. (US) | 2010-07-27 | — | — | US | disclosed |
| CN-101779124-A | modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC | 2010-07-14 | — | — | CN | disclosed |
| CN-101519372-A | Benzo [e] isoindazole-1,3 diketone compound used as GSK inhibiting agent and preparation method thereof | SHENZHEN SHENGJIE BIOLOGY TECH | 2009-09-02 | — | — | CN | disclosed |
| US-20030013881-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2003-01-16 | — | — | US | disclosed |
| EP-1265849-A2 | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002098849-A2 | HYDROXY ALKYL AMINE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND THEIR USE FOR THE TREATMENT OF ALZHEIMER’S DISEASE AND SIMILAR DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020022623-A1 | Compounds to treat alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2002-02-21 | — | — | US | disclosed |
| US-20020019403-A1 | Methods to treat alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2002-02-14 | — | — | US | disclosed |
| WO-2001070672-A2 | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| US-6140014-A | MULTILAYER ELEMENT, PHOTOSENSITIVE COMPOSITION WITH GRAINS ON SURFACES | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0841190-B1 | Lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0841190-A1 | Lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-3983230-A | HALF ESTERS WITH DICARBOXYLIC ACIDS, MEDICAMENTS | SHIONOGI & CO., LTD. (JA) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019403-A1 | Methods to treat alzheimer's disease | PSEN1, PSEN2, BACE1 | TPMT 1971/4885ALDH1A1 214/4885MEN1 2214/4885 |
| US-20030013881-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, BACE1 | TPMT 2413/4885ALDH1A1 463/4885MEN1 1764/4885 |
| US-20020022623-A1 | Compounds to treat alzheimer's disease | PSEN1, PSEN2, BACE1 | TPMT 2177/4885ALDH1A1 165/4885MEN1 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.