Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673921 | 0.89 | KDM4E (0.34) | GAAL3MBTL1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10815985 | 0.87 | CYP4F2 (0.41) | GAAL3MBTL1POLBHSD17B10ALDH1A1 | |
| SCHEMBL10398085 | 0.86 | GAA (0.38) | GAAL3MBTL1POLBHSD17B10ALDH1A1 | |
| SCHEMBL10398506 | 0.86 | GAA (0.38) | GAAL3MBTL1POLBHSD17B10ALDH1A1 | |
| SCHEMBL11199031 | 0.84 | GAA (0.40) | GAAL3MBTL1POLBHSD17B10KDM4E | |
| SCHEMBL11202548 | 0.83 | GAA (0.39) | GAAL3MBTL1POLBHSD17B10KDM4E | |
| SCHEMBL11200164 | 0.83 | GAA (0.39) | GAAL3MBTL1POLBHSD17B10NR4A2 | |
| SCHEMBL11202739 | 0.82 | GAA (0.39) | GAAL3MBTL1POLBHSD17B10NR4A2 | |
| SCHEMBL3987342 | 0.80 | KDM4E (0.41) | GAAL3MBTL1POLBHSD17B10ALDH1A1 | |
| SCHEMBL10814009 | 0.80 | KMT2A (0.35) | GAAL3MBTL1POLBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937368-A | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4835288-A | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates | SYNTEX INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0275092-A1 | Process for preparing (+)-1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole-1,7-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1988-07-20 | — | — | EP | disclosed |