Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202548 | 0.96 | GAA (0.39) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL10815985 | 0.92 | CYP4F2 (0.41) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL11200164 | 0.88 | GAA (0.39) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL11202739 | 0.86 | GAA (0.39) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL10397397 | 0.84 | GAA (0.38) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL10398085 | 0.84 | GAA (0.38) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL10398506 | 0.84 | GAA (0.38) | GAACYP4A11CYP4F2NR4A2L3MBTL1 | |
| SCHEMBL11195432 | 0.82 | GAA (0.36) | GAANR4A2L3MBTL1KDM4EBRD4 | |
| SCHEMBL11195237 | 0.81 | GAA (0.35) | GAANR4A2L3MBTL1KDM4EBRD4 | |
| SCHEMBL3987342 | 0.79 | KDM4E (0.41) | GAACYP4A11CYP4F2NR4A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |