SCHEMBL1039749

SCHEMBL1039749

Cc1ccccc1O[Si](Oc1ccccc1C)(Oc1ccccc1C)Oc1ccccc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
ACHE P22303 1/20 0.45
ALDH1A1 P00352 3/20 0.42
GLA P06280 1/20 0.41
CYP1A2 P05177 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
SCN4A P35499 1/20 0.38
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10574340 0.88 TSHR (0.47) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL5001938 0.88 TSHR (0.47) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL11210716 0.83 SMN1; SMN2 (0.42) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL1053023 0.82 TSHR (0.50) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL10913475 0.82 TSHR (0.50) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL8418620 0.82 TSHR (0.50) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL31036946 0.82 TSHR (0.50) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL9777926 0.80 TSHR (0.48) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL5604779 0.80 TSHR (0.48) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL1054766 0.77 TSHR (0.45) TSHRSMN1; SMN2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085733-B2 Yttrium aluminum garnet phosphor, method for preparing the same, and light-emitting diode containing the same NATIONAL CHENG KUNG UNIVERSITY (TW) 2015-07-21 US claimed
US-20130146918-A1 Yttrium aluminum garnet phosphor, method for preparing the same, and light-emitting diode containing the same NATIONAL CHENG KUNG UNIVERSITY (TW) 2013-06-13 US claimed
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US claimed
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed
EP-3916045-B1 HIGH STRENGTH HYDROGENATED POLYMERS, AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP disclosed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP disclosed
US-20250215210-A1 DIENE RUBBER COMPOSITION AND METHOD FOR PRODUCING SAME ETIC INC. (JP) 2025-07-03 US disclosed
US-20250109282-A1 NATURAL RUBBER COMPOSITIONS FOR PNEUMATIC TIRES BRIDGESTONE CORPORATION (JP) 2025-04-03 US disclosed
WO-2025049846-A1 HYDROGENATED POLYMERS PRODUCED USING ANTIOXIDANT, AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-03-06 WO disclosed
EP-0581611-A2 Process for preparing polyolefins NIPPON OIL Co. Ltd. (JP) 1994-02-02 EP disclosed
EP-0263516-B1 A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION CATALYSTS TOHO TITANIUM CO. LTD. (JP) 1992-04-22 EP disclosed
US-4942148-A COORDINATION CATALYLTS OF METAL OXIDE, ORGANOMAGNESIUM COMPOUNDS, AN ORGANOALUMINUM COMPOUND, A TITANIUM COMPOUND AND ELECTRON DONOR COMPOUND TOA NENRYO KOGYO, K.K. (JP) 1990-07-17 US disclosed
US-4839321-A COORDINATION CATALYST CONTAINING DIETHOXY MAGNESIUM, CALCIUM CHLORIDE, SILICON COMPOUND, TITANIUM TETRACHLORIDE, AROMATIC DIESTER, AND ORGANOALUMINUM COMPOUND TOHO TITANIUM CO., LTD. (JP) 1989-06-13 US disclosed
EP-0312314-A1 Catalyst component for olefin polymerization Tonen Corporation (JP) 1989-04-19 EP disclosed
EP-0263516-A2 A solid catalyst component for olefin polymerization catalysts TOHO TITANIUM CO. LTD. (JP) 1988-04-13 EP disclosed
US-4072636-A ORGANO-SILICATE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-02-07 US disclosed