Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039749 | 0.80 | TSHR (0.52) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10913475 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL31036946 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1053023 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL8418620 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9777926 | 0.76 | TSHR (0.48) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10574340 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5001938 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1054766 | 0.73 | TSHR (0.45) | TSHRSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3804301 | 0.73 | SMN1; SMN2 (0.45) | TSHRSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447066-B2 | Pneumatic tyres | BRIDGESTONE CORP (JP) | 2000-08-16 | — | — | EP | claimed |
| US-5409969-A | Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene | BRIDGESTONE CORPORATION (JP) | 1995-04-25 | — | — | US | claimed |
| EP-0447066-A1 | Pneumatic tyres | Bridgestone Corporation (JP) | 1991-09-18 | — | — | EP | claimed |
| US-20070208126-A1 | Vulcanizable rubber composition, in particular for low rolling resistance treads of vehicle tires | PIRELLI PNEUMATICI S.P.A. | 2007-09-06 | — | — | US | disclosed |
| US-20040220324-A1 | First modified conjugated diolefin-vinylaromatic copolymer; second conjugated diolefin-vinylaromatic copolymer; first carbon black-based reinforcing filler; second silica-based reinforcing filler | PIRELLI PNEUMATICI S.P.A. | 2004-11-04 | — | — | US | disclosed |
| EP-0972790-B1 | Process for producing a vulcanizable rubber composition including carbon black-based and silicia-based reinforcing fillers | PIRELLI (IT) | 2004-09-22 | — | — | EP | disclosed |
| EP-1189767-B1 | LOW ROLLING RESISTANCE TIRE FOR VEHICLES | PIRELLI (IT) | 2004-07-28 | — | — | EP | disclosed |
| EP-0934973-B1 | Vulcanizable rubber composition, in particular for low rolling resistance treads of vehicle tires | PIRELLI PNEUMATICIS P A (IT) | 2004-04-28 | — | — | EP | disclosed |
| US-6624233-B2 | Mechanical properties | PIRELLI PNEUMATICI S.P.A. (IT) | 2003-09-23 | — | — | US | disclosed |
| US-20020143096-A1 | Low rolling resistance tire for vehicles | PIRELLI PNEUMATICI S.P.A. (IT) | 2002-10-03 | — | — | US | disclosed |
| US-20020107317-A1 | VULCANIZABLE RUBBER COMPOSITION, IN PARTICULAR FOR LOW ROLLING RESISTANCE TREADS OF VEHICLE TIRES | PIRELLI PNEUMATICI S.P.A (IT) | 2002-08-08 | — | — | US | disclosed |
| EP-0447066-B2 | Pneumatic tyres | BRIDGESTONE CORP (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0972790-A1 | Process for producing a vulcanizable rubber composition including carbon black-based and silicia-based reinforcing fillers | PIRELLI PNEUMATICI Società per Azioni (IT) | 2000-01-19 | — | — | EP | disclosed |
| EP-0934973-A1 | Vulcanizable rubber composition, in particular for low rolling resistance treads of vehicle tires | PIRELLI PNEUMATICI S.p.A. (IT) | 1999-08-11 | — | — | EP | disclosed |
| US-5496883-A | COMPRISING TREAD RUBBER OF POLYBUTADIENE POLYMER OR COPOLYMER CONTAINING SILICA AND MODIFIED WITH SILANE COUPLING AGENT; COUPLING AGENT; WET SKID RESISTANCE, LOW ROLLLING RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5409969-A | Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene | BRIDGESTONE CORPORATION (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0299074-B1 | TIRE | Bridgestone Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5066721-A | TIRES MADE OF SILICA FILLED, SILANE MODIFIED RUBBER | BRIDGESTONE CORPORATION (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0447066-A1 | Pneumatic tyres | Bridgestone Corporation (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0299074-A1 | TIRE | Bridgestone Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |