SCHEMBL10397669

SCHEMBL10397669

CC(=CC=C(c1ccccc1)c1ccccc1)C(=O)NCCCCc1cccnc1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 19/20 0.69
EPHX2 P34913 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397667 1.00 PTAFR (0.69) PTAFREPHX2
SCHEMBL9520861 0.81 PTAFR (1.00) PTAFR
SCHEMBL9520848 0.81 PTAFR (1.00) PTAFR
SCHEMBL10398641 0.81 PTAFR (1.00) PTAFR
SCHEMBL10472058 0.81 PTAFR (1.00) PTAFREPHX2
SCHEMBL10469996 0.80 PTAFR (0.98) PTAFREPHX2
SCHEMBL10471146 0.80 PTAFR (0.81) PTAFREPHX2
SCHEMBL10470437 0.77 PTAFR (1.00) PTAFREPHX2
SCHEMBL10399104 0.76 PTAFR (0.94) PTAFR
SCHEMBL10471549 0.76 PTAFR (0.94) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975438-A ANTICOAGULANT HOFFMANN-LA ROCHE INC. (US) 1990-12-04 US disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed