SCHEMBL10399104

SCHEMBL10399104

COc1ccc(/C(=C\C=C\C(=O)NCCCCc2cccnc2)c2ccccc2)cc1

nearest known ligand 0.94

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 20/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9519479 0.97 PTAFR (1.00) PTAFR
SCHEMBL9519484 0.97 PTAFR (1.00) PTAFR
SCHEMBL9519646 0.96 PTAFR (0.94) PTAFR
SCHEMBL9522644 0.96 PTAFR (0.94) PTAFR
SCHEMBL9519636 0.96 PTAFR (0.94) PTAFR
SCHEMBL9522654 0.92 PTAFR (0.95) PTAFR
SCHEMBL9522661 0.92 PTAFR (0.95) PTAFR
SCHEMBL10399331 0.92 PTAFR (0.95) PTAFR
SCHEMBL9520848 0.91 PTAFR (1.00) PTAFR
SCHEMBL9520861 0.91 PTAFR (1.00) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975438-A ANTICOAGULANT HOFFMANN-LA ROCHE INC. (US) 1990-12-04 US disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed