Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397765 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9628370 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL10398216 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL10397439 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9626899 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9626805 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9626605 | 1.00 | THRA (0.48) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9627299 | 0.93 | PTPN11 (0.43) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL10397764 | 0.93 | PTPN11 (0.43) | THRATHRBPTPN11MAPTPTPN1 | |
| SCHEMBL9627426 | 0.92 | THRA (0.48) | THRATHRBPTPN11MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |