SCHEMBL10397706

SCHEMBL10397706

C=C/C=C(/C(=O)NC(C)CCCc1cccnc1)c1ccc(F)cc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397710 1.00 PTAFR (0.66) PTAFR
SCHEMBL10398979 0.82 PTAFR (0.69) PTAFR
SCHEMBL10398982 0.82 PTAFR (0.69) PTAFR
SCHEMBL10399003 0.80 PTAFR (1.00) PTAFR
SCHEMBL9521018 0.80 PTAFR (1.00) PTAFR
SCHEMBL9519576 0.80 PTAFR (1.00) PTAFR
SCHEMBL10472766 0.78 PTAFR (0.62) PTAFR
SCHEMBL10514360 0.77 PTAFR (0.63) PTAFR
SCHEMBL10673055 0.76 PTAFR (0.70) PTAFR
SCHEMBL10459235 0.76 PTAFR (0.84) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975438-A ANTICOAGULANT HOFFMANN-LA ROCHE INC. (US) 1990-12-04 US disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed