Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 17/20 | 0.84 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459236 | 1.00 | PTAFR (0.84) | PTAFRNAMPTLMNA | |
| SCHEMBL10459771 | 0.89 | PTAFR (0.81) | PTAFR | |
| SCHEMBL10459769 | 0.89 | PTAFR (0.81) | PTAFR | |
| SCHEMBL10459774 | 0.83 | PTAFR (0.76) | PTAFR | |
| SCHEMBL10459775 | 0.83 | PTAFR (0.76) | PTAFR | |
| SCHEMBL10459683 | 0.83 | PTAFR (0.82) | PTAFR | |
| SCHEMBL10459682 | 0.83 | PTAFR (0.82) | PTAFR | |
| SCHEMBL10459669 | 0.81 | PTAFR (0.81) | PTAFRLMNA | |
| SCHEMBL10459902 | 0.81 | PTAFR (0.73) | PTAFRLMNA | |
| SCHEMBL10459904 | 0.81 | PTAFR (0.73) | PTAFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |