SCHEMBL10398153

SCHEMBL10398153

Oc1ccc(CN2CCOCC2)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.66
ALOX15 P16050 1/20 0.66
HSD17B10 Q99714 1/20 0.66
CYP2A13 Q16696 6/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C19 P33261 1/20 0.53
GAA P10253 2/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CTSB P07858 1/20 0.51
POLB P06746 1/20 0.48
TYR P14679 1/20 0.47
ACHE P22303 2/20 0.47
BCHE P06276 1/20 0.47
BACE1 P56817 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL11148661 0.94 CYP2C9 (0.58) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL30830470 0.87 CYP2C9 (0.62) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL23235219 0.87 CYP2C9 (0.62) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL8800403 0.86 CTSB (0.62) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL2025162 0.83 CYP2C9 (0.66) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL2013061 0.83 CYP2C9 (0.62) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL11148657 0.83 SMN1; SMN2 (0.59) CYP2C9ALOX15HSD17B10CYP2D6KDM4E
SCHEMBL2509364 0.82 MAOB (0.63) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL2509369 0.82 MAOB (0.63) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4
SCHEMBL13339132 0.82 MAOB (0.63) CYP2C9ALOX15HSD17B10CYP2A13CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0122523-A2 Diazotype compositions and materials Andrews Paper and Chemical Co., Inc. (US) 1984-10-24 EP claimed
EP-1893207-B1 USE OF SUBSTITUTED PIPERAZINE DERIVATIVES AND MORPHOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-08-03 EP disclosed
US-4929534-A DEVELOPER RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0305873-A2 Positive photosensitive composition and photosensitive registration material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-08 EP disclosed