SCHEMBL10398373

SCHEMBL10398373

Cc1ccc(O)c2nn[nH]c12

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC6A2 P23975 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28114612 0.83 KDM4E (0.31)
SCHEMBL4017003 0.83 MAPT (0.31)
SCHEMBL9951516 0.76 KDM4E (0.39)
SCHEMBL6729678 0.76 IDO1 (0.39)
SCHEMBL9951570 0.72 LMNA (0.32) HTT
SCHEMBL6052108 0.71 COMT (0.45) KMT2A
SCHEMBL9174801 0.69 COMT (0.44) KMT2A
SCHEMBL10627192 0.69 MAPT (0.46) OPRK1KMT2AHTT
SCHEMBL9172490 0.68 MAPT (0.45) OPRK1KMT2AHTT
SCHEMBL6275824 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929534-A DEVELOPER RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0305873-A2 Positive photosensitive composition and photosensitive registration material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-08 EP disclosed