Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403601 | 0.79 | TSHR (0.35) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL27850967 | 0.76 | KDM4E (0.37) | MTNR1AMTNR1BCTSSCTSKMCL1 | |
| SCHEMBL3117585 | 0.75 | CYP2D6 (0.50) | MCL1CYP2D6CYP2C19 | |
| SCHEMBL6269500 | 0.74 | — | — | |
| SCHEMBL1962382 | 0.71 | — | — | |
| SCHEMBL17260751 | 0.71 | — | — | |
| SCHEMBL8436259 | 0.70 | MAPK1 (0.40) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL9884583 | 0.70 | MAPK1 (0.40) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL26490723 | 0.70 | MAPK1 (0.45) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| Ammonia Solution, Strong SCHEMBL5709315 | 0.70 | TDP1 (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929534-A | DEVELOPER RESISTANCE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |