Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884583 | 0.95 | MAPK1 (0.40) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL22668470 | 0.88 | ALDH1A1 (0.38) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL22668616 | 0.88 | ALDH1A1 (0.38) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL13655846 | 0.86 | TSHR (0.40) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL25724405 | 0.84 | ALDH1A1 (0.39) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL18502830 | 0.84 | ALDH1A1 (0.39) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL2105851 | 0.83 | TSHR (0.57) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL18638052 | 0.83 | TSHR (0.57) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL13950295 | 0.80 | PAOX (0.39) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL14397158 | 0.80 | PAOX (0.39) | MAPK1KDM4EHIF1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202874-A1 | FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS | BP ASSET V, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| CN-101462994-B | Vitamin D derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2012-11-28 | — | — | CN | disclosed |
| CN-102617690-A | Vitamin d derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2012-08-01 | — | — | CN | disclosed |
| US-20100093645-A1 | SMAC Peptidomimetics and the Uses Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-04-15 | — | — | US | disclosed |
| US-20100093645-A1 | SMAC Peptidomimetics and the Uses Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-04-15 | — | — | US | disclosed |
| EP-1383731-B1 | BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS | BIOCRYST PHARM INC (US) | 2009-08-05 | — | — | EP | disclosed |
| CN-101462994-A | Vitamin D derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | CN | disclosed |
| CN-100469764-C | Vitamin D derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| WO-2007117241-A1 | INTRAMUSCULAR ANTIVIRAL TREATMENTS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007095218-A1 | INTRAVENOUS ANTIVIRAL TREATMENTS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | WO | disclosed |
| CN-1436170-A | vitamin D derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-08-13 | — | — | CN | disclosed |
| EP-0777658-B1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| US-5885934-A | HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| EP-0777658-A1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005179-A1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093645-A1 | SMAC Peptidomimetics and the Uses Thereof | BID, AIFM1, BAD | MAPK1 2134/4885KDM4E 3557/4885HIF1A 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.