Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 20/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519636 | 1.00 | PTAFR (0.94) | PTAFR | |
| SCHEMBL9519646 | 1.00 | PTAFR (0.94) | PTAFR | |
| SCHEMBL9519479 | 0.97 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9519484 | 0.97 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10399104 | 0.96 | PTAFR (0.94) | PTAFR | |
| SCHEMBL10399205 | 0.91 | PTAFR (0.89) | PTAFR | |
| SCHEMBL9519588 | 0.89 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9519600 | 0.89 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9521343 | 0.89 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9519892 | 0.89 | PTAFR (0.85) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |