Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603592 | 1.00 | KAT8 (0.48) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL7602848 | 1.00 | KAT8 (0.48) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL20615288 | 0.94 | BACE1 (0.45) | KAT8TYRALOX5HTTESR1 | |
| SCHEMBL21289229 | 0.89 | BACE1 (0.41) | KAT8TYRALOX5KDM4EALDH1A1 | |
| SCHEMBL21569772 | 0.84 | TYR (0.42) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1024794 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL8392959 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL11781504 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL8390293 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL1023097 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923909-A | THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |