Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602848 | 1.00 | KAT8 (0.48) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL10399116 | 1.00 | KAT8 (0.48) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL20615288 | 0.94 | BACE1 (0.45) | KAT8TYRALOX5HTTESR1 | |
| SCHEMBL21289229 | 0.89 | BACE1 (0.41) | KAT8TYRALOX5KDM4EALDH1A1 | |
| SCHEMBL21569772 | 0.84 | TYR (0.42) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1024794 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL8392959 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL11781504 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL8390293 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 | |
| SCHEMBL1023097 | 0.82 | KAT8 (0.61) | KAT8TYRTP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451888-B1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6033600-A | PENTAERYTHRITOL PHOSPHITE, A HINDERED PHENOLIC ISOCYANURATE, A METAL SALT OF A FATTY ACID AND HYDROTALCITE. | GENERAL ELECTRIC COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0685516-B1 | Solid stabilizer composition with improved hydrolytic stability | GEN ELECTRIC (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0685516-A1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5162406-A | Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol | THE DOW CHEMICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0106169-B1 | SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF | The B.F. GOODRICH Company (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0128368-B1 | 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES | The B.F. GOODRICH Company (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4529533-A | Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| US-4522735-A | Polyphosphoramidite oligomers and stabilizer compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4495320-A | 3,6-Di-t-butyl-2-naphthyl catechol phosphite and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0128368-A1 | 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes | The B.F. GOODRICH Company (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4472548-A | HYDROXYPHENYLALKYL ISOCYANURATE, STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0110293-A2 | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | The B.F. GOODRICH Company (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0106169-A1 | Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4444929-A | Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations | THE B. F. GOODRICH COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| EP-0104643-A2 | 5-Membered cyclic phosphonates and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4439564-A | 5-Membered cyclic phosphonates and compositions thereof | THE B. F. GOODRICH CO. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4415686-A | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| US-4025486-A | PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1977-05-24 | — | — | US | disclosed |