Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399963 | 0.89 | HTT (0.31) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9868886 | 0.85 | HTT (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27300317 | 0.83 | MEN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10400551 | 0.80 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10400526 | 0.80 | CYP2C19 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10400265 | 0.77 | POLB (0.34) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL10400029 | 0.76 | HTT (0.39) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL10400883 | 0.74 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27293150 | 0.74 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10595985 | 0.72 | POLB (0.40) | KMT2AALDH1A1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973600-A | CONGESTIVE HEART FAILURE, GOUT, DIRUETICS, HYPERURICEMIA | TANABE SEIYAKU CO., LTD. (JP) | 1990-11-27 | — | — | US | claimed |
| EP-0329326-A1 | Benzodioxole derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-23 | — | — | EP | claimed |
| US-4973600-A | CONGESTIVE HEART FAILURE, GOUT, DIRUETICS, HYPERURICEMIA | TANABE SEIYAKU CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4965282-A | DIURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0329326-A1 | Benzodioxole derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |