Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399155 | 1.00 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL2813142 | 0.85 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL2813135 | 0.85 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL27766998 | 0.80 | EPHX2 (0.41) | RAB9A | |
| SCHEMBL14678383 | 0.79 | CA1 (0.58) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL27909884 | 0.77 | AKT1 (0.47) | CA1CA2PARP1MAPK1HSD17B10 | |
| SCHEMBL27766838 | 0.75 | HDAC3 (0.44) | PRSS1PRSS2PRSS3 | |
| SCHEMBL10685379 | 0.74 | ALDH1A1 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL24205454 | 0.74 | CA1 (0.51) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL30924784 | 0.74 | MAPT (0.47) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | claimed |
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |