Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398955 | 1.00 | PTAFR (0.53) | PTAFRCNR1CNR2TP53TSHR | |
| SCHEMBL10399186 | 1.00 | PTAFR (0.53) | PTAFRCNR1CNR2TP53TSHR | |
| SCHEMBL10398907 | 1.00 | PTAFR (0.53) | PTAFRCNR1CNR2TP53TSHR | |
| SCHEMBL10398954 | 1.00 | PTAFR (0.53) | PTAFRCNR1CNR2TP53TSHR | |
| SCHEMBL10398908 | 1.00 | PTAFR (0.53) | PTAFRCNR1CNR2TP53TSHR | |
| SCHEMBL10399228 | 0.99 | PTAFR (0.52) | PTAFRCNR1CNR2PDE4BTHRB | |
| SCHEMBL10399227 | 0.99 | PTAFR (0.52) | PTAFRCNR1CNR2PDE4BTHRB | |
| SCHEMBL10399226 | 0.99 | PTAFR (0.52) | PTAFRCNR1CNR2PDE4BTHRB | |
| SCHEMBL10399322 | 0.95 | PTAFR (0.52) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10399321 | 0.95 | PTAFR (0.52) | PTAFRPDE4BTHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |