Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 7/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399322 | 1.00 | PTAFR (0.52) | PTAFRPDE4BKDM4ECRHBPHTT | |
| SCHEMBL10399226 | 0.96 | PTAFR (0.52) | PTAFRPDE4BKDM4ECRHBPHTT | |
| SCHEMBL10399227 | 0.96 | PTAFR (0.52) | PTAFRPDE4BKDM4ECRHBPHTT | |
| SCHEMBL10399228 | 0.96 | PTAFR (0.52) | PTAFRPDE4BKDM4ECRHBPHTT | |
| SCHEMBL10399183 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10398908 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10398954 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10398907 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10399186 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM | |
| SCHEMBL10398955 | 0.95 | PTAFR (0.53) | PTAFRPDE4BTHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |