Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941071 | 1.00 | CES2 (0.56) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3940143 | 1.00 | CES2 (0.56) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3944593 | 0.97 | MAOB (0.55) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3944597 | 0.97 | MAOB (0.55) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL4098610 | 0.89 | RXFP1 (0.46) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL4098608 | 0.89 | RXFP1 (0.46) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3938860 | 0.86 | KDM4E (0.49) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3938858 | 0.86 | KDM4E (0.49) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL3938865 | 0.86 | KDM4E (0.49) | CES2MAOBSRD5A2ALDH1A1LMNA | |
| SCHEMBL4093274 | 0.85 | CES2 (0.53) | CES2MAOBSRD5A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |