Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735833 | 0.88 | KMT2A (0.39) | ALDH1A1KMT2ADPP7SIGMAR1RIPK2 | |
| SCHEMBL530785 | 0.88 | — | — | |
| SCHEMBL818299 | 0.78 | — | — | |
| SCHEMBL538845 | 0.78 | — | — | |
| SCHEMBL5863700 | 0.77 | EPHX2 (0.38) | ALDH1A1KMT2ADPP7SIGMAR1OPRM1 | |
| SCHEMBL20651185 | 0.77 | KMT2A (0.42) | KMT2ANPSR1DPP7SIGMAR1 | |
| SCHEMBL368439 | 0.77 | HTR1A (0.35) | KMT2ADPP7SIGMAR1 | |
| SCHEMBL5863695 | 0.77 | EPHX2 (0.38) | ALDH1A1KMT2ADPP7SIGMAR1OPRM1 | |
| SCHEMBL4900932 | 0.77 | KMT2A (0.33) | KMT2ADPP7SIGMAR1RIPK2 | |
| SCHEMBL20870846 | 0.77 | RIPK2 (0.33) | ALDH1A1KMT2ANPSR1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892918-A | TOUGHENING THERMOSETTING MATRIX RESINS | BASF CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| US-4847154-A | Thermosetting resin systems containing secondary amine-terminated siloxane modifiers | BASF CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0312771-A1 | Thermosetting resin systems containing secondary amine-terminated siloxane modifiers | BASF Aktiengesellschaft (DE) | 1989-04-26 | — | — | EP | disclosed |