Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 1.00 |
| ▸ | TYMS | P04818 | 5/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.61 |
| ▸ | PARP1 | P09874 | 4/20 | 0.61 |
| ▸ | TNKS | O95271 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850811 | 0.90 | QTRT1 (0.81) | QTRT1TYMSTNKS2PARP1TNKS | |
| SCHEMBL28693661 | 0.88 | QTRT1 (0.78) | QTRT1TYMSTNKS2PARP1TNKS | |
| SCHEMBL6695759 | 0.79 | TNKS2 (0.81) | QTRT1TNKS2PARP1TNKSPKM | |
| SCHEMBL4311562 | 0.77 | TYMS (0.71) | QTRT1TYMSPARP1 | |
| SCHEMBL30249625 | 0.77 | TYMS (0.71) | QTRT1TYMSPARP1 | |
| SCHEMBL6654365 | 0.77 | TYMS (1.00) | QTRT1TYMS | |
| SCHEMBL30589037 | 0.77 | TYMS (1.00) | QTRT1TYMS | |
| SCHEMBL894736 | 0.76 | TNKS2 (0.61) | QTRT1TNKS2PARP1TNKSPKM | |
| SCHEMBL22807316 | 0.76 | TNKS2 (0.61) | QTRT1TNKS2PARP1TNKSPKM | |
| SCHEMBL22021640 | 0.76 | TNKS2 (0.61) | QTRT1TNKS2PARP1TNKSPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015063544-A1 | NOVEL SUBSTITUTED 2-AMINOQUINAZOLIN-4(3H)-ONE DERIVATIVES AS MALARIAL ASPARTIC PROTEASE INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2015-05-07 | — | — | WO | claimed |
| CN-1956721-A | Quinazolinone derivatives as vanilloid antagonists | NOVARTIS AG (CH) | 2007-05-02 | — | — | CN | claimed |
| US-4226994-A | BUTANOL SOLVENT, ANTHRANILIC ACID, CYANAMIDE, HYDRAZINE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-10-07 | — | — | US | claimed |
| CN-120157674-A | New preparation method of domperidone | 刘辉 | 2025-06-17 | — | — | CN | disclosed |
| EP-4334305-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116096710-A | 4-oxo-3, 4-dihydroquinazolinone compounds for the treatment of BRAF related diseases and disorders | 阿雷生物药品公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3675858-B1 | IMIDAZO[1,5-A]PYRAZINE COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION | OPTIKIRA LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| CN-114230557-B | Quinazoline-substituted 1,2,3-triazole derivative, and pharmaceutical composition, preparation method and application thereof | 深圳大学 | 2023-01-06 | — | — | CN | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-5166315-A | Polynucleotides for genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064833-A | Substituted quinazoline derivatives for use in gastrointestinal diseases | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0322133-B1 | QUINAZOLINE DERIVATIVES | SmithKline Beecham Intercredit B.V. (NL) | 1991-05-22 | — | — | EP | disclosed |
| EP-0322133-A1 | Quinazoline derivatives | SmithKline Beecham Intercredit B.V. (NL) | 1989-06-28 | — | — | EP | disclosed |
| WO-1989005297-A1 | COMPOUNDS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-06-15 | — | — | WO | disclosed |
| CN-1033380-A | Compound | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-06-14 | — | — | CN | disclosed |
| US-4226994-A | BUTANOL SOLVENT, ANTHRANILIC ACID, CYANAMIDE, HYDRAZINE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| US-3867384-A | 2-Amino-4(3H)-quinazolinones | BULLOCK GREG A | 1975-02-18 | — | — | US | disclosed |
| US-3867384-A | 2-Amino-4(3H)-quinazolinones | BULLOCK GREG A | 1975-02-18 | — | — | US | disclosed |