QTRT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL21067387	0.76	2/20
SCHEMBL4308775	0.33	2/20
SCHEMBL30583529	0.33	2/20
SCHEMBL4316132	0.32	2/20
SCHEMBL103994	1.00	1/20
SCHEMBL21067931	1.00	1/20
SCHEMBL29941448	1.00	1/20
SCHEMBL29850811	0.81	1/20
SCHEMBL21068028	0.79	1/20
SCHEMBL29941519	0.79	1/20
SCHEMBL28693661	0.78	1/20
SCHEMBL6695759	0.66	1/20
SCHEMBL4311562	0.62	1/20
SCHEMBL30249625	0.62	1/20
SCHEMBL6654365	0.62	1/20
SCHEMBL30589037	0.62	1/20
SCHEMBL29723934	0.61	1/20
SCHEMBL47352	0.61	1/20
SCHEMBL146025	0.61	1/20
SCHEMBL577954	0.61	1/20

Clinical trials — most relevant to QTRT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Assessment of Artesunate/Mefloquine in the Peruvian Amazon	PHASE4	COMPLETED
Primaquine Double Dose for Radical Cure of Plasmodium Vivax in Colombia	PHASE2/PHASE3	WITHDRAWN
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies	PHASE1/PHASE2	RECRUITING
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor	PHASE1/PHASE2	NOT_YET_RECRUITING
NEO100 and High-Grade Meningioma	PHASE2	RECRUITING
Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer	PHASE2	COMPLETED
Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and Lymphomas	PHASE1	COMPLETED
Genetic Variability in CYP2D6 in U.S Active Duty Population	PHASE1	COMPLETED
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects	PHASE1	COMPLETED
Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors	PHASE1	COMPLETED
The Effect of Intermittent Rifampicin on Raltegravir	PHASE1	COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors	PHASE1	COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma	PHASE1	WITHDRAWN
Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers	PHASE1	COMPLETED
Antimalarial Drug Resistance in Mali	nan	COMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives	nan	UNKNOWN
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer	nan	UNKNOWN
Choroid Plexus Dysfunction in Neurological Diseases	nan	RECRUITING
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients.	nan	UNKNOWN
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar	nan	COMPLETED
Prevalence of Congenital Long QT Syndrome and Acquired QT Prolongation in a Hospital Cohort	nan	COMPLETED
Mitoquines in COPD	nan	UNKNOWN
Long QT Syndrome-Population Genetics and Cardiac Studies	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Telomeres Length in Israeli Fibrotic ILD Patients	nan	ENROLLING_BY_INVITATION
Sirtuin1 in COVID19 Patients	nan	UNKNOWN
Evaluation of Genetic-molecular Causes of Out-of-Hospital Cardiac Arrest: From Patients to Families	nan	RECRUITING
The Effects of the Anesthetic Drug Propofol on the Way the Heart Recovers Between Beats	nan	COMPLETED
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
Telomere Disclosure and Impact on Psychological Distress and Health Behaviors	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a QTRT1 binder may also engage these)

Protein	Name	Similarity
Q28HC6	—	1.000	Q28HC6 →
Q9VPY8	—	0.999	Q9VPY8 →
Q4QQY7	—	0.998	Q4QQY7 →
Q9JMA2	—	0.998	Q9JMA2 →
O94460	—	0.998	O94460 →
Q7SYK1	—	0.997	Q7SYK1 →
A8X0P0	—	0.996	A8X0P0 →
Q4QR99	—	0.994	Q4QR99 →
Q23623	—	0.988	Q23623 →
B7UVU4	—	0.988	B7UVU4 →
A9AW42	—	0.987	A9AW42 →
Q3SH61	—	0.987	Q3SH61 →
Q02RX7	—	0.986	Q02RX7 →
Q2G639	—	0.986	Q2G639 →
Q87EW6	—	0.985	Q87EW6 →
A1TVN0	—	0.985	A1TVN0 →
Q5P720	—	0.985	Q5P720 →
Q9HXH9	—	0.985	Q9HXH9 →
P28720	—	0.984	P28720 →
A1VFP3	—	0.984	A1VFP3 →
B2I6T4	—	0.983	B2I6T4 →
Q42954	—	0.983	Q42954 →
C4XSI9	—	0.983	C4XSI9 →
A6U2A7	—	0.983	A6U2A7 →
C0QKY2	—	0.983	C0QKY2 →
A5ITG3	—	0.983	A5ITG3 →
Q9RRB5	—	0.983	Q9RRB5 →
Q63707	—	0.983	Q63707 →
Q82VF0	—	0.982	Q82VF0 →
Q5QVL2	—	0.982	Q5QVL2 →